Only one of the Y chromosome genes, the SRY gene, is responsible for male anatomical traits. Females have two X chromosomes in their cells, while males have X and Y chromosomes in their cells. However, about 10 percent of carrier females have less than half the normal amount of one of these coagulation factors; these individuals are at risk for abnormal bleeding, particularly after an injury, surgery, or tooth extraction. This is called "skewed X-inactivation. National Library of Medicine Figure However, the Y chromosome doesn't contain most of the genes of the X chromosome.
X-linked traits are maternally inherited from carrier mothers or from an affected father. She passed the harmful allele for this X-linked trait on to one of her four sons and at least two of her five daughters. But in recessive inheritance, both matching genes must be abnormal to cause disease. Other genes on the Y chromosome are important for male fertility. Most of the Y chromosome genes are involved with essential cell house-keeping activities 16 genes and sperm production 9 gene families. There are a few Y-linked traits; these are inherited by sons from their father. An abnormal gene on the X chromosome from each parent would be required, since a female has two X chromosomes. There is, however, one exception to this: Queen Victoria with her husband and nine children in By comparison to the X chromosome, the much smaller Y chromosome has only about 26 genes and gene families. Males have only one X chromosome. Colorblindness is another example of a sex-linked trait in humans. However, the genes on the Y chromosome are a major exception. The two gametes came together during fertilization to produce a diploid individual. X and Y are sex chromosomes. Creasy and Resnik's Maternal-Fetal Medicine: By the early 20th century, ten of Victoria's descendents had hemophilia. However, about 10 percent of carrier females have less than half the normal amount of one of these coagulation factors; these individuals are at risk for abnormal bleeding, particularly after an injury, surgery, or tooth extraction. Each daughter born to a affected father and a non-carrier mother will be a carrier. Female carriers can have a normal X chromosome that is abnormally inactivated. Serious complications can result from bleeding into the joints, muscles, brain, or other internal organs. The Y chromosome is the other half of the XY gene pair in the male. In each pregnancy, if the mother is a carrier and the father has the disease, the expected outcomes are: URL of this page: In addition to 22 homologous pairs of autosomes, human females have a homologous pair of X chromosomes, whereas human males have an XY chromosome pair. A B C Illustration of some X-linked heredity outcomes A the affected father has one X-linked dominant allele, the mother is homozygous for the recessive allele:
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