The overall number of transfusions per patient-day in the ICU averaged 0. Published online Apr A similar ANOVA was performed for specific disease categories including multiple trauma, respiratory diseases, cardiovascular diseases and postoperative patients in order to control for the influence of disease categories on transfusion thresholds. For the bedside questionnaire, we determined the response rate at each institution by cross checking recorded transfusions in the cohort study with the completed questionnaires. Prompted by concerns over transfusion-related infections, recent guidelines emphasize that the decision to transfuse should not be determined by a single haemoglobin concentration [ 4 , 5 , 6 ].
In this study, no adjustments were made for multiple comparisons. Statistical analysis Descriptive statistical analyses were performed on all variables in each component of this study. Psychology Today does not warrant or represent that Psychology Today directory or any part thereof is accurate or complete. Physicians requesting the transfusion were then asked to identify the most important reason for the administration of red cells from a list of nine possible choices: Each bedside questionnaire was administered within 24 h of the request for a transfusion. To determine how transfusion status received or did not receive red cells , the institution as well as previously defined age ranges and APACHE II categories influenced pre-transfusion haemoglobin concentrations, we performed a four-way ANOVA. We collected demographic and transfusion-related information as well as data on patient outcomes and disease severity. The lowest overall haemoglobin concentration in patients who were not transfused or the haemoglobin concentration recorded prior to the administration of red cells in patients receiving blood were labelled pre-transfusion haemoglobin and were used as the primary outcome in the study. Sample size considerations The size of the cohort study was based on pre-transfusion haemoglobin concentrations as an outcome. For patients receiving multiple transfusion episodes in a h period only the first request was analysed. A preliminary analysis of the influence of diagnostic categories on the administration of red cells was evaluated using a chi-square statistic. Table 1 Characteristics of patients included in the cohort study Institution. Published online Apr Chi-square procedures were employed to test relationships between the nine clinical factors and other variables such as transfusion thresholds and diagnostic categories as well as the level of training of physicians responding to the questionnaire. Physicians who wrote transfusion orders were asked if they initiated the request or if another physician requested the administration of red cells. The overall number of transfusions per patient-day in the ICU averaged 0. Neither the importance of a specific transfusion threshold nor the clinical characteristics that influence transfusion practice have been documented in this high-risk patient population. Psychology Today disclaims all warranties, either express or implied, including but not limited to the implied warranties of merchantability and fitness for particular purpose. The term 'transfusion threshold' was defined as the pre-transfusion haemoglobin concentration recorded in the bedside questionnaire. Multicentre cohort study combined with a cross-sectional survey of physicians requesting red cell transfusions for patients in the cohort. The cohort included consecutive patients admitted to six tertiary level intensive care units in addition to administering a survey to physicians requesting red cell transfusions in these units. Inclusion in Psychology Today does not imply recommendation or endorsement nor does omission from Psychology Today imply Psychology Today disapproval. This study was therefore designed to characterize actual transfusion practice, to determine whether there is any significant institutional practice variation and reasons why red cells are administered in critically ill patients. Patients who were less than 16 years of age or who were considered brain dead within 24 h of admission were excluded. When you see this seal, it means Psychology Today has verified the following: The name and contact details of the professional That the professional's license, if applicable, is valid within the province in which he or she practices That the professional is not subject to any license strictures preventing practice Psychology Today verifies the information at the time a therapist is initially listed in the directory and then upon expiration of the professional's credentials.
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