Comment on the video. JoJojas 3 months ago I'm not a "cause a fit" type of person either. The tra-2 gene of C. The completed construct was purified by CsCl ultracentrifugation The Fem1b gene was targeted for inactivation by homologous recombination using a well-established general strategy Breeding and experiments with mice were approved by our local Institutional Animal Care and Use Committee.
Shak 5 months ago Agree. Vishura 4 months ago An interesting question there is: The Fem1b gene is highly expressed in INS-1E insulinoma cells, a widely used cell culture model of regulated insulin secretion. Mammalian homologs of nematode sex determination genes have recently been implicated in glucose homeostasis and type 2 diabetes mellitus. The tra-2 gene of C. The initial report identifying the NIDDM1 gene as Calpain recognized that this atypical calpain protease has homology to the nematode tra-3 gene In the studies described herein, we have used gene targeting by homologous recombination to generate Fem1b knockout Fem1b-KO mice with inactivation of the Fem1b gene. The completed construct was purified by CsCl ultracentrifugation Keep up the good work. Mammalian homologs of two other nematode sex determination genes, tra-2 and tra-3, have recently been implicated in glucose homeostasis and type 2 diabetes mellitus. The fem-1 gene of Caenorhabditis elegans encodes an ankyrin repeat protein that is part of a signal transduction and transcriptional regulatory pathway controlling cell fate decisions during sex determination in the nematode 10 , 17 , It's possible that I haven't been forceful enough with them, and they just aren't Brall 3 months ago You do this obnoxious number quite competently. These are the Hedgehog receptor Patched and Calpain, which have homology to the nematode tra-2 and tra-3 sex determination genes, respectively. Arashir 4 months ago Not sure I follow your comment. Akizshura All that borrowing was money spent elsewhere. Yes, genome commonality between species correlates to the phylogenic classification which supports the theory of evolution. The mammalian Fem1 genes are expressed in tissues of relevance to glucose physiology, including pancreas and skeletal muscle. In producing susceptibility to type 2 diabetes mellitus, NIDDM1 is known to interact with a gene, whose identity is unknown, on human chromosome 15 near the CYP19 locus at 15q You're close to earning an in-person assignment on BART. For example, looking at a specific gene and comparing its presence in other species correlates to the phylogenic distance as well. We need to pay for sh! The Fem1b gene was targeted for inactivation by homologous recombination using a well-established general strategy In other words the gene shows up more in species that are closer to humans that is does in species that are more distant evolutionarily. The nematode sex determination pathway may be a variant of Hedgehog signaling Arginine-stimulated insulin secretion is also affected. JoJojas 3 months ago I'm not a "cause a fit" type of person either.
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